The U.S.-Japan Cooperative Medical Sciences Program
 
Cholera and Other Bacterial Enteric Infections Agenda
February 9-10, 2017
Novotel Ambassador Seoul Gangnam Hotel - Champagne B, 2nd Floor
 
 
 
THURSDAY 2/9/2017
Morning
US-Japan Joint Panel Conference on Cholera and Other Bacterial Enteric Infections
Welcome: Dr. John D. Clemens, Executive Director, icddr,b
 
08:00 -- 08:30
 
REGISTRATION
 
Moderators:
Dr. John D. Clemens & Dr. Mitsuaki Nishibuchi
1
08:30 08:50
John Mekalanos
The role of Type VI secretion in antagonistic interactions between different bacterial species in the small Intestine
 
2
 
08:50 09:10
 
Tadashi Shimamoto
Functional analysis of hypothetical gene orf205 in retron-Vc95 of Vibrio cholerae O1 El Tor and O139
 
3
 
09:10 09:30
 
Minmin Yen
Impact of virulent bacteriophages on Vibrio cholerae infection and their use in preventing cholera
 
4
 
09:30 09:50
 
Sirajul Islam
Interepidemic reservoir, endemicity and seasonality of cholera in Bangladesh
 
5
 
09:50 10:10
 
Mohammad Ali
 
Identification of hotspots and risk factors for cholera in India
10:10 10:30
Coffee Break
 
Moderators:
Dr. Masatoshi Noda & Dr. John Mekalanos
 
6
 
10:30 -- 10:50
 
Christine Marie George
Genetic relatedness of Vibrio cholerae isolates during outbreaks in Dhaka, Bangladesh
 
7
 
10:50 11:10
 
Daryl Domman
 
High resolution genomic view of cholera within Dhaka city
 
8
 
11:10 -- 11:30
 
Mouhaman Arabi
A spatial analysis of cholera risk in a sahelian urban environment: case of Maroua, Cameroon
 
9
 
11:30 11:50
 
Marco Salemi
Molecular Epidemiology of toxigenic V. cholerae O1 in Haiti: Strain movement between clinical and environmental sources
 
10
 
11:50 12:10
 
Japheth Opintan
Phylogeographic and antimicrobial drug resistance analysis of Vibrio cholerae O1 in Accra, Ghana
 
11
 
12:10 12:30
 
Tetsu Yamashiro
Community based cohort study on diarrheal diseases in an agricultural village in northern Vietnam
12:30 -- 13:30
Lunch
LUNCH

 
THURSDAY 2/9/2017
Afternoon
US-Japan Joint Panel Conference on Cholera and Other Bacterial Enteric Infections
 
Moderators:
Dr. Firdausi Qadri & Dr. Tetsuya Iida
 
12
 
13:30 13:50
 
Shota Nakamura
Type IV pilus structure and assembly of human enterotoxigenic
Escherichia coli
 
13
 
13:50 14:10
 
Weiping Zhang
MEFA (multiepitope fusion antigen), a novel structure-based design for developing broadly protective vaccines against enterotoxigenic Escherichia coli (ETEC)
 
14
 
14:10 14:30
 
Subhra Chakraborty
Impact of host factors in predicting clinical diarrhea outcome after infection with enterotoxigenic E. coli in humans
 
15
 
14:30 14:50
 
Hoang Hoai Phuong
Effect of orally administered Cefoperazone (CFP) on intestinal colonization of ESBL-producing Escherichia coli in mice
 
16
 
14:50 -- 15:10
 
Sho Hatayama
The relation of cellular tight junctions formation and Campylobacter jejuni invasion in intestinal epithelial cells
15:10– 15:30
Coffee break
 
COFFEE BREAK
Moderators:
Dr. Shinji Yamasaki & Dr. Mohammad Ali
 
17
 
15:30 15:50
 
Neelam Taneja
Evolution of antimicrobial resistance in Shigella since the turn of 21st century, India
 
18
 
15:50 16:10
 
Ahmad Yaman Kayali
Updates of the IMS (immunomagnetic separation)– LAMP (loop-mediated isothermal amplification)–based detection method for enterohaemorrhagic Escherichia coli belonging to 15 O serotypes
 
19
 
16:10 16:30
 
Hermanta Koley
Heat-killed multi serotype Shigella immunogens induce Th1 and Th17 cell mediated adaptive immune responses in mice model
 
20
 
16:30 -- 16:50
 
Kimitoshi Ichimura
Nitric oxide-enhanced Shiga toxin production was regulated by Fur and RecA in enterohemorrhagic Escherichia coli O157
 
21
 
16:50 -- 17:10
 
Asish Mukhopadhyay
Pathogenic modulation in El Tor vibrios: evidence from recent Indian strains harbouring Haitian traits
 
22
 
17:10 -- 17:30
 
Eiki Yamasaki
Quantitative detection of Shiga toxins directly from stool specimens of patients associated with an outbreak of enterohemorrhagic Escherichia coli in Japan
17:30 Adjourn

 
Friday 2/10/2017
Morning
US-Japan Joint Panel Conference on Cholera and Other Bacterial Enteric Infections
 
Moderators:
Dr. Daniel Leung & Dr. Tetsu Yamashiro
23
08:30 08:50
 
Sharda Prasad Awasthi
 
 
Expression level of cholix toxin varies among Vibrio cholerae strains
 
 
24
 
08:50 09:10
 
Stefan Karlsson
 
 
 
Transcriptome analysis shows differences between isogenic Ogawa and Inaba derivatives of O1 Vibrio cholerae
 
 
25
 
09:10 09:30
 
Jayedul Hassan
 
 
Isolation and characterization of cytolethal distending toxin-producing Providencia rustigianii from a diarrheal child in Japan
 
 
26
 
09:30 09:50
 
Shah Faruque
 
 
Emerging diversity of the CRISPR/Cas system in cholera phages
 
 
27
 
09:50 10:10
 
Matthew Dorman
 
 
CRISPR/Cas systems are not detectable in El Tor lineages of Vibrio cholerae
 
10:10 10:40
Coffee Break
 
Moderators:
Dr. Mitsuaki Nishibuchi & Dr. Asish Mukhopadhyay
 
 
28
 
10:40 11:00
 
Md Taufiqur Rahman Bhuiyan
 
 
Single cell analysis of the plasmablast response to Vibrio cholerae demonstrates expansion of cross-reactive memory B cells
 
 
29
 
11:00 11:20
 
Richelle Charles
 
 
The plasma and mucosal antibody response to the complete Vibrio cholerae O1 protein immunome and O-specific polysaccharide in adults with Inaba or Ogawa cholera in Bangladesh
 
 
30
 
11:20 -- 11:40
 
Richelle Charles
 
 
Plasma and memory B cell responses targeting O-specific polysaccharide (OSP) are associated with protection against Vibrio cholerae O1 infection among household contacts of cholera patients in Bangladesh
 
 
31
 
11:40 12:00
 
Kamrul Islam
 
 
Immune responses against O-specific polysaccharide (OSP) develop after vaccination with oral cholera vaccine CVD 103-HgR (Vaxchora) and these responses are associated with protection against experimental infection with Vibrio cholerae O1 El Tor Inaba in North American volunteers
 
 
32
 
12:00 – 12:20
 
Daniel Leung
 
 
Dried blood spots: an alternate tool for the assessment of immune response to cholera infection and vaccine
 
12:20 -- 13:20
Lunch
LUNCH

 
FRIDAY 2/10/2017
Afternoon
US-Japan Joint Panel Conference on Cholera and Other Bacterial Enteric Infections
 
Moderators:
Dr. David Sack & Dr. Masatoshi Noda
33
13:20 -- 13:40
Raphael Fando
Oral cholera vaccine development in Cuba: advances and challenges
34
13:40 -- 14:00
Tarun Sharma
Development of affordable single strain oral cholera vaccine
35
14:00 -- 14:20
Firdausi Qadri
Oral cholera vaccine studies in Bangladesh and the way forward
 
36
 
14:20 -- 14:40
 
Khalid Ali Syed
Study to evaluate safety, tolerability and immunogenicity of two formulations of inactivated (Hikojima serotype) novel oral cholera vaccine, Hillchol.
 
37
 
14:40 -- 15:00
 
Allyson Nelson
 
Safety of a killed oral cholera vaccine (Shanchol) in pregnant women in Malawi: An observational cohort study
15:00 15:30
Coffee break
 
COFFEE BREAK
Moderators:
Dr. Tetsuya Iida & Dr. Raphael Fando
 
38
 
15:30 --15:50
 
Moise C. Ngwa
Cultural influences behind cholera transmission in the Far North Region, Republic of Cameroon: a field experience and implications for operational level planning of interventions
 
39
 
15:50 -- 16:10
 
John Clemens
Evaluation of newer generation cholera vaccines: is a new paradigm needed?
 
 
40
 
 
16:10 -- 16:30
 
 
Wataru Yamazaki
Campylobacter prevalence in broiler flocks highly correlates with food poisoning frequency in Japan: assessment in broiler cecal and fecal samples by conventional culture and loopmediated isothermal amplification methods
41
16:30 -- 16:50
Sean Moore
El Niño and the shifting geography of cholera in Africa
 
42
 
16:50 -- 17:10
 
Justin Im
Typhoid and iNTS disease burden in pre-school children in Africa: Results from the Typhoid Surveillance in Africa Program (TSAP)
Final Words and Adjournment
Dr. John D. Clemens & Dr. Mitsuaki Nishibuchi
 
Announcing:
The 2018 U.S. Japan Conference on Cholera & Other Bacterial Enteric Infections